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1314009

USP

Hydrochlorothiazide

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide

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About This Item

Fórmula empírica (notación de Hill):
C7H8ClN3O4S2
Número de CAS:
58-93-5
Peso molecular:
297.74
MDL number:
MFCD00051765
UNSPSC Code:
41116107
PubChem Substance ID:
329750021
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

hydrochlorothiazide

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl

InChI

1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)

InChI key

JZUFKLXOESDKRF-UHFFFAOYSA-N

Gene Information

human ... SLC12A3(6559)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrochlorothiazide USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, standard stock, system suitability, Hydrochlorothiazide standard solutions for assay, performance, and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
  • Hydrochlorothiazide Capsules
  • Amiloride Hydrochloride and Hydrochlorothiazide Tablets
  • Captopril and Hydrochlorothiazide Tablets

Biochem/physiol Actions

Carbonic anhydrase inhibitor

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H351

Hazard Classifications

Carc. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Captopril and Hydrochlorothiazide Tablets
United States Pharmacopeia, 43(4), 737-737 (2019)
Amiloride Hydrochloride and Hydrochlorothiazide Tablets
United States Pharmacopeia, 44(3), 224-224 (2019)
Hydrochlorothiazide Capsules
United States Pharmacopeia, 44(1), 2219-2219 (2019)
Franz H Messerli et al.
The American journal of medicine, 124(10), 896-899 (2011-10-04)
Hydrochlorothiazide (HCTZ) has become by far the most commonly prescribed antihypertensive drug in the US. In 2008, 47.8 million prescriptions were written for HCTZ alone and 87.1 million prescriptions for HCTZ combinations. However, there is no evidence that HCTZ in
Dragos Vinereanu et al.
American heart journal, 168(4), 446-456 (2014-09-30)
The objective of this study is to compare the effects of 2 types of diuretics, indapamide and hydrochlorothiazide, added to an angiotensin-converting enzyme inhibitor, on ventricular and arterial functions in patients with hypertension and diabetes. This is a prospective, randomized
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