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Merck

BP1101

Sulfato de hidroxicloroquina

British Pharmacopoeia (BP) Reference Standard

Sinónimos:

Sulfato de 7-cloro-4-[4-(N-etil-N-b-hidroxietilamino)-1-metilbutilamino]quinolina

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About This Item

Fórmula empírica (notación de Hill):
C18H26ClN3O · H2SO4
Número de CAS:
Peso molecular:
433.95
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

agency

BP

API family

hydroxychloroquine

form

solid

shelf life

limited shelf life, expiry date on the label

packaging

pkg of 25 mg

manufacturer/tradename

BP

storage condition

OK to freeze

color

off-white

mp

238-241 °C

solubility

water: soluble

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

shipped in

ambient

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

InChI key

JCBIVZZPXRZKTI-UHFFFAOYSA-N

Gene Information

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General description

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol (Hydroxychloroquine Sulfate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Biochem/physiol Actions

El sulfato de hidroxicloroquina es un antiinflamatorio (vía TNF), un antirreumático modificador de la enfermedad (DMARD) y un inhibidor de la hemo polimerasa. Se utiliza para tratar el paludismo.

Packaging

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Hydroxychloroquine Sulfate
British Pharmacopeia, 2021
British Pharmacopoeia, 44(12), 1000-1004 (2021)
Seminars in Arthritis and Rheumatism, 43(2), 264-272 (2013)
Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
Charlier B,et al.
Biomedical Chromatography, 32(8), e4258-e4258 (2018)
A rapid and reliable method for the quantitation of hydroxychloroquine in serum using turbulent flow liquid chromatography-tandem mass spectrometry
Fuzery AK, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 421 (2013)
Compatibility study of hydroxychloroquine sulfate with pharmaceutical excipients using thermal and nonthermal techniques for the development of hard capsules
Moraes ANF, et al.
Journal of Thermal Analysis and Calorimetry, 421 (2019)

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