SML0737

MitoTEMPO

≥98% (HPLC), powder, antioxidant

• Sinónimos: (2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chloride, Mito-TEMPO
• Fórmula empírica (notación de Hill): C₂₉H₃₅N₂O₂P · Cl
• Número de CAS: 1334850-99-5
• Peso molecular: 510.03
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Nombre del producto: MitoTEMPO, ≥98% (HPLC)
• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• condiciones de almacenamiento: desiccated; protect from light
• color: white to light brown
• solubilidad: H₂O: 10 mg/mL, clear
• temp. de almacenamiento: −20°C
• cadena SMILES: [P+](CC(=O)NC4CC(N(C(C4)(C)C)[O])(C)C)(c3ccccc3)(c2ccccc2)c1ccccc1.[Cl-]
• InChI: 1S/C29H34N2O2P.ClH/c1-28(2)20-23(21-29(3,4)31(28)33)30-27(32)22-34(24-14-8-5-9-15-24,25-16-10-6-11-17-25)26-18-12-7-13-19-26;/h5-19,23H,20-22H2,1-4H3;1H
• Clave InChI: WKKFJIJNGHNQQW-UHFFFAOYSA-N

Descripción

Aplicación

MitoTEMPO has been used as a mitochondria-targeted antioxidant.

Acciones bioquímicas o fisiológicas

MitoTEMPO is a mitochondrially targeted antioxidant, a specific scavenger of mitochondrial superoxide.

MitoTEMPO is a mitochondrially targeted antioxidant, a specific scavenger of mitochondrial superoxide. MitoTEMPO is a combination of the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, giving MitoTEMPO the ability to pass through lipid bilayers with ease and accumulate several hundred-fold in mitochondria. Mitochondrial dysfunction and oxidative stress contribute to a variety of disorders involving cardiovascular, kidney, liver disorders, Parkinson′s and Alzheimer′s disease.

Otras notas

Light sensitive

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable