581500

TEMPOL

≥95% (HPLC), crystals,powder, free radical scavenger and nitric oxide spin trap, Calbiochem^®

• Sinónimos: TEMPOL, 4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
• Fórmula empírica (notación de Hill): C₉H₁₈NO₂
• Número de CAS: 2226-96-2
• Peso molecular: 172.24
• Número MDL: MFCD00006478
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Nombre del producto: TEMPOL, A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.
• Nivel de calidad: 100
• descripción: RTECS - TN8991000
• Ensayo: ≥95% (HPLC)
• Formulario: crystals; powder
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: orange
• solubilidad: DMSO: 5 mg/mL; ethanol: soluble; water: soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• cadena SMILES: [N+]1(C(CC(CC1(C)C)O)(C)C)[O-]
• InChI: 1S/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3
• Clave InChI: UZFMOKQJFYMBGY-UHFFFAOYSA-N

Descripción

Descripción general

A stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21^WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.

Acciones bioquímicas o fisiológicas

Cell permeable: yes

Primary Target
Free radical scavenger and nitric oxide spin trap

Product does not compete with ATP.

Reversible: no

Envase

Packaged under inert gas

Advertencia

Toxicity: Harmful (C)

Reconstitución

Prepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).

Otras notas

Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med.29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo)41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS08,GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H302,H318,H373
• Consejos de prudencia: P260 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P314
• Clasificaciones de peligro: Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2 Oral
• Órganos de actuación: Liver,spleen
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 294.8 °F - DIN 51758
• Punto de inflamabilidad (°C): 146 °C - DIN 51758