SAB5801058

Goat Anti-Rabbit IgG(Fcγ) Alpaca Heavy chain only Antibody

recombinant Alpaca(VHH) Nano antibody

• Sinónimos: Recombinant Alpaca single variable domain secondary Nanobody
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: alpaca
• recombinant: expressed in HEK 293 cells (Human cell line)
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: secondary antibodies
• clone: recombinant monoclonal
• form: lyophilized solid
• mol wt: 100 kDa
• species reactivity: Alpaca, rabbit
• technique(s): ELISA: 1:10000-1:50000; western blot: 1:10000-1:50000
• size: 0.1 mL
• color: colorless
• isotype: VHH
• shipped in: wet ice
• storage temp.: 2-8°C

Descripción

General description

Goat Anti-Rabbit IgG(Fcγ) Alpaca Heavy chain only Antibody is designed to specifically detect Fc region of rabbit IgG Fcγ fragment. It is a monovalent, single domain, recombinant antibody fused to goat IgG Fc. Based on immunoelectrophoresis and/or ELISA, Goat Anti-Rabbit IgG(Fcγ) Alpaca Heavy chain only Antibody reacts with the Fc region of rabbit IgG selectively but not with mouse, human, cynomolgus, rat, goat IgG.
Rabbit research antibodies are widely used in life science research. So far, four isotypes have been identified (IgA, IgE, IgG, and IgM) in rabbits. Each isotype has a different heavy chain. Rabbit has only one IgG subclass. The whole IgG molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgG contains two heavy and light chains. The heavy chain is about 50 KD and the light chain is about 25 KD. The common IgG is monomeric with a molecular weight of approximately 150 kD.
VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.

Specificity

Fc region of Rabbit IgG
Isotype: VHH domain of alpaca IgG2b/2c fused to goat IgG Fc

Immunogen

Recombinant Alpaca single variable domain secondary nano antibody

Packaging

100 μg in Glass bottle

Physical form

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

Reconstitution

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

Storage and Stability

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Stable for 12 months at -20°C

Other Notes

No cross-reactivity with mouse, human, cynomolgus, rat, goat IgG

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H317,H412
• pcodes: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 3 - Skin Sens. 1
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable