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Merck
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Key Documents

P1750

Sigma-Aldrich

Pancreatina from porcine pancreas

4 × USP specifications

Sinónimos:

Pancreatina from hog pancreas

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About This Item

Número de CAS:
8049-47-6
EC Number:
232-468-9
MDL number:
MFCD00131789
UNSPSC Code:
12352204
NACRES:
NA.54

agency

USP (specifications)

Quality Level

200

form

powder

specific activity

4 × USP specifications

contains

lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)

storage temp.

−20°C

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Application

Pancreatin from porcine pancreas has been used:
  • for a study to assess the treatment of steatorrhea by lipase supplementation therapy
  • for a study to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis
  • to safely and effectively remove formalin-fixed tissues from arterial grafts without causing structural damage and loss in fiber integrity
  • to assess cleavage by digestive enzymes.
  • for in vitro digestibility analysis and to test the sensitivities of cellulolytic bacteria inhibitors.
  • along with amyloglucosidase for the in vitro digestion of starch in food samples.

Biochem/physiol Actions

La pancreatina contiene componentes enzimáticos, como la tripsina, la amilasa y las lipasas, las ribonucleasas y las proteasas, producidas por las células exocrinas de páncreas porcino. Esta combinación de enzimas permite hidrolizar las proteínas, el almidón y las grasas. La pancreatina convertirá no menos de 25 veces su peso de almidón de patata en carbohidratos solubles en 5 minutos en agua a 40 °C, digerirá no menos de 25 veces su peso de caseína en 60 minutos a pH 7,5 a 40 °C y liberará no menos de microequivalentes de ácido por minuto por miligramo de pancreatina del aceite de oliva a pH 9,0 y 37 °C.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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David C Whitcomb et al.
Digestive diseases and sciences, 52(1), 1-17 (2007-01-06)
A primary function of the pancreas is to produce digestive enzymes that are delivered to the small intestine for the hydrolysis of complex nutrients. Much of our understanding of digestive enzymes comes from studies in animals. New technologies and the
Ying Ma et al.
Journal of dairy science, 104(1), 47-60 (2020-11-10)
Infant formula is used as a supplement for newborns. Although bovine milk-based infant formulas dominate the market, caprine milk-based infant formula has attracted increasing attention because of its lower allergenicity. This study compared the digestive peptidome of bovine and caprine
Oluwafunmilayo O Adeleye et al.
Heliyon, 6(11), e05419-e05419 (2020-11-24)
African yam beans (Sphenostylis stenocarpa), Bambara groundnut (Vigna subterranean) and Pigeon pea (Cajanus cajan) flours were extruded in a single screw extruder at two extrusion temperatures; 100 °C and 140 °C, and the effect of extrusion cooking temperature on the
T Nakamura et al.
Pancreas, 16(3), 329-336 (1998-04-21)
Pancreatic steatorrhea and pancreatic diabetes are the dominant symptoms of patients in the decompensated stage of chronic pancreatitis (CP). In this stage, the nutritional state is greatly disturbed and hypoglycemia and labile infection are involved. Pancreatic enzyme replacement therapy is
Peter Layer et al.
Pancreas, 26(1), 1-7 (2002-12-25)
Treatment of steatorrhea by lipase supplementation therapy has become more successful in the last decade due to better understanding of the physiology and pathophysiology of the digestive process. Porcine lipase has been the therapeutic standard for several decades and will
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