O2136

Oleamide

≥99% (TLC), powder, sleep-inducing brain lipid

• Sinónimos: cis-9,10-Octadecenoamide, cis-9-Octadecenamide, Oleic acid amide
• Fórmula empírica (notación de Hill): C₁₈H₃₅NO
• Número de CAS: 301-02-0
• Peso molecular: 281.48
• Número CE: 206-103-9
• Número MDL: MFCD00053638
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24897957
• NACRES: NA.77

Propiedades

• Nombre del producto: Oleamide, ≥99%
• Nivel de calidad: 200
• Ensayo: ≥99%
• control farmacológico: regulated under CDSA - not available from Sigma-Aldrich Canada
• temp. de almacenamiento: −20°C
• cadena SMILES: CCCCCCCC\C=C/CCCCCCCC(N)=O
• InChI: 1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
• Clave InChI: FATBGEAMYMYZAF-KTKRTIGZSA-N

Descripción

Descripción general

Oleamide is a lipid or a brain fatty acid, that is found in the CSF (cerebrospinal fluid). It is originally obtained from the cerebrospinal fluid of cats, that are sleep-deprived.

Aplicación

Oleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).

Acciones bioquímicas o fisiológicas

Oleamide has the ability to stimulate sleep. It possess several properties, like cannabinoid-like activity. Oleamide can also disable the communication, facilitated by gap junction between rat glial cells.

Sleep-inducing brain lipid, which allosterically modulates GABA_A receptors and potentiates 5-HT₇ serotonin receptor responses. Selective endogenous agonist of rat and human CB1 cannabinoid receptor.

Información de seguridad

• Frases de peligro: H413
• Consejos de prudencia: P273 - P501
• Clasificaciones de peligro: Aquatic Chronic 4
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 404.6 °F - closed cup
• Punto de inflamabilidad (°C): 207 °C - closed cup
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves