Saltar al contenido
Merck

I1877

Sigma-Aldrich

Isocitric Dehydrogenase (NADP) from porcine heart

Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)

Sinónimos:

threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH, IDH

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Número de CAS:
Comisión internacional de enzimas:
EC Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54

biological source

Porcine heart

Quality Level

type

Type I

form

solid

specific activity

0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)

storage temp.

−20°C

¿Está buscando productos similares? Visita Guía de comparación de productos

Biochem/physiol Actions

Isocitrate dehydrogenase (IDH) plays a major role in the Krebs cycle by catalyzing the oxidative decarboxylation of isocitrate. The oxidative decarboxylation of isocitrate generates α-ketoglutarate and NADPH. NADPH produced is essential for the production of fatty acids and cholesterol. This NADP-dependent molecules serves as homodimers.

Quality

Crude

Unit Definition

One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

The Molecular Pathogenesis of Glioblastoma
Glioblastoma, 21-31 (2016)
Molecular Testing for Glioblastoma
Diagnostic Molecular Pathology, 339-347 (2017)
Chapter One - Mechanisms of Epigenetic Regulation of Leukemia Onset and Progression
Ntziachristos P, et al.
Advances in Immunology, 117, 1-38 (2013)
Omar Abdel-Wahab et al.
Hematology. American Society of Hematology. Education Program, 2012, 56-64 (2012-12-13)
The myelodysplastic syndromes (MDS) are a clinically and cytogenetically heterogeneous group of clonal diseases characterized by ineffective hematopoiesis, peripheral blood cytopenias, and an increased risk of progression to acute myeloid leukemia. The precise molecular mechanisms behind the development of MDS
Maria Paola Martelli et al.
Blood reviews, 27(1), 13-22 (2012-12-25)
Acute myeloid leukemia (AML) is a molecularly heterogeneous disease. Based on cytogenetics and FISH, AML patients are stratified into three major risk categories: favourable, intermediate and unfavourable. However, prognostic stratification and treatment decision for the intermediate risk category, that mostly

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico