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Merck

E2511

Sigma-Aldrich

ExtrAvidin®

essentially salt-free, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

form

essentially salt-free, lyophilized powder

Quality Level

technique(s)

dot blot: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
radioimmunoassay: suitable

shipped in

wet ice

storage temp.

2-8°C

Specificity

Binding Activity: at least 10 μg biotin per mg

Application

ExtrAvidin® has been used to tetramerize aliquots to generate HLA-A2 tetramers.

Biochem/physiol Actions

ExtrAvidin® is prepared from egg white avidin. It is a tetrameric protein containing four high affinity binding sites for biotin. It combines the high specific activity of avidin with the low background staining of streptavidin, a biotin binding protein produced by the bacteria Streptomyces avidinii. It binds biotin with the high affinity of egg white avidin, however, it does not exhibit the unwanted non-specific binding reported for egg white avidin at physiological pH, such as the staining of mast cells.

Other Notes

A modified form of affinity purified egg white avidin.

Legal Information

ExtrAvidin is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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