Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

D0390

Sigma-Aldrich

NG,NG′-Dimethyl-L-arginine di(p-hydroxyazobenzene-p′-sulfonate) salt

≥99% (TLC)

Sinónimos:

SDMA

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C8H18N4O2 · 2C12H10N2O4S
Número de CAS:
1266235-58-8
Peso molecular:
758.82
UNSPSC Code:
12352202
PubChem Substance ID:
329798603
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

assay

≥99% (TLC)

form

powder

solubility

methanol: 10 mg/mL

storage temp.

room temp

SMILES string

CN\C(NC)=N\CCC[C@H](N)C(O)=O.Oc1ccc(cc1)\N=N\c2ccc(cc2)S(O)(=O)=O.Oc3ccc(cc3)\N=N\c4ccc(cc4)S(O)(=O)=O

InChI

1S/2C12H10N2O4S.C8H18N4O2/c2*15-11-5-1-9(2-6-11)13-14-10-3-7-12(8-4-10)19(16,17)18;1-10-8(11-2)12-5-3-4-6(9)7(13)14/h2*1-8,15H,(H,16,17,18);6H,3-5,9H2,1-2H3,(H,13,14)(H2,10,11,12)/b2*14-13+;/t;;6-/m..0/s1

InChI key

HISUXCNNXYEHER-YJSASASGSA-N

Application

Plasma sym-dimethylarginine has been considered a marker of hepatic and renal dysfunction. A sensitive LC-MS method for identifying arginine, and both asym- and sym-dimethylarginine in plasma and urine samples has been developed.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Lena Pelander et al.
Journal of veterinary internal medicine, 33(2), 630-639 (2019-02-23)
Early detection of decreased glomerular filtration rate (GFR) in dogs is challenging. Current methods are insensitive and new biomarkers are required. To compare overall diagnostic performance of serum symmetric dimethylarginine (SDMA) and serum cystatin C to serum creatinine, for detection
Jane Yu et al.
Animals : an open access journal from MDPI, 10(6) (2020-06-12)
The pharmacokinetic profile of mefloquine was investigated as a preliminary study towards a potential treatment for feline coronavirus infections (such as feline infectious peritonitis) or feline calicivirus infections. Mefloquine was administered at 62.5 mg orally to seven clinically healthy cats
Shahrbanou Javadiyan et al.
Investigative ophthalmology & visual science, 53(4), 1923-1927 (2012-03-08)
Asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are the dimethylated isomeric derivatives of the amino acid L-arginine. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS), while SDMA is a competitive inhibitor of cellular uptake of L-arginine, the substrate
Eva Buresova et al.
Journal of veterinary internal medicine, 33(2), 516-522 (2019-01-12)
Measurement of serum creatinine (sCr) and urea nitrogen fail to detect decreased renal function in many hyperthyroid cats because of low muscle mass and glomerular hyperfiltration of affected cats. Serum symmetric dimethylarginine (sSDMA) is an earlier and more sensitive renal
Olga Kruszelnicka et al.
Amino acids, 47(9), 1951-1959 (2015-04-11)
Metformin, the drug of first choice in type 2 diabetes mellitus (T2DM), reduces cardiovascular (CV) morbidity and mortality in part independently of improved glycemic control and changes in traditional risk factors. However, there are discordant reports on the effects of
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico