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A3085

Sigma-Aldrich

5-(N-Ethyl-N-isopropyl)amiloride

≥98% (TLC), powder, Na⁺/H⁺ antiport inhibitor

Sinónimos:

EIPA

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About This Item

Fórmula empírica (notación de Hill):
C11H18ClN7O
Número de CAS:
1154-25-2
Peso molecular:
299.76
MDL number:
MFCD00151710
UNSPSC Code:
12352200
PubChem Substance ID:
24278223
NACRES:
NA.77

product name

5-(N-Ethyl-N-isopropyl)amiloride,

biological source

synthetic

Quality Level

200

assay

≥98% (TLC)

form

powder

mp

202-205 °C (lit.)

solubility

methanol: 9.80-10.20 mg/mL, clear, light yellow to yellow

storage temp.

2-8°C

SMILES string

CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N

InChI

1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)

InChI key

QDERNBXNXJCIQK-UHFFFAOYSA-N

Gene Information

human ... SCNN1A(6337) , SCNN1B(6338) , SCNN1D(6339) , SCNN1G(6340) , SLC9A1(6548) , SLC9A5(6553)
mouse ... Scnn1a(20276) , Scnn1b(20277) , Scnn1d(140501) , Scnn1g(20278)
rat ... Scnn1a(25122) , Scnn1b(24767) , Scnn1g(24768) , Slc9a1(24782) , Slc9a2(24783) , Slc9a3(24784) , Slc9a4(24785)

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Application

5-(N-Ethyl-N-isopropyl)amiloride has been used:
  • as a supplement in endothelial cell growth medium to incubate human lung microvascular endothelial cell
  • in Pluronic F-127 stock solution for Drosophila larval live-imaging
  • in choline chloride solution as an experimental perfusate, to study the effect of Na+/H+ inhibition on jejunal loop perfusion in vivo

Biochem/physiol Actions

Selective blocker of Na+/H+ antiport

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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