86339

Sodium taurocholate hydrate

≥97.0% (TLC)

• Sinónimos: Taurocholic acid sodium salt
• Fórmula empírica (notación de Hill): C₂₆H₄₄NNaO₇S · xH₂O
• Número de CAS: 345909-26-4
• Peso molecular: 537.68 (anhydrous basis)
• Beilstein/REAXYS Number: 3901620
• EC Number: 205-653-7
• MDL number: MFCD00150819
• UNSPSC Code: 12161902
• PubChem Substance ID: 57653098
• NACRES: NA.77

Propiedades

• biological source: ox bile; synthetic
• Quality Level: 200
• description: anionic
• assay: ≥97.0% (TLC)
• form: powder
• optical activity: [α]20/D +23±1°, c = 3% in H₂O (dry matter)
• mol wt: 537.68 g/mol (anhydrous basis)
• impurities: ≤1% taurine; ≤2% cholic acid
• solubility: H₂O: 50 mg/mL, clear
• functional group: sulfonic acid
• SMILES string: O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1
• InChI key: RDAJAQDLEFHVNR-NEMAEHQESA-M

Descripción

Application

Sodium taurocholate hydrate was used as an emulsifier in in situ preparation of digestive enzymes.

Biochem/physiol Actions

Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid. These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.

Preparation Note

Sodium taurocholate hydrate yields a clear, colorless solution in water at 50 mg/ml.

Other Notes

For the solubilization of unconjugated bilirubin

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)