PHR1799

Meloxicam

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: Meloxicam, 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
• Fórmula empírica (notación de Hill): C₁₄H₁₃N₃O₄S₂
• Número de CAS: 71125-38-7
• Peso molecular: 351.40
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to BP 629; traceable to Ph. Eur. Y0001080; traceable to USP 1379401
• familia API: meloxicam
• CofA: current certificate can be downloaded
• envase: pkg of 500 mg
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,19H,1-2H3,(H,15,16)/b13-11+
• Clave InChI: DWMREKMVXIFPFM-ACCUITESSA-N

Descripción

Descripción general

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Meloxicam is an oxicam derivative and belongs to the group of non-steroidal anti-inflammatory drugs (NSAID), used for its analgesic, anti-inflammatory, and antipyretic properties. It acts by inhibiting the activity of prostaglandin synthetase, thereby preventing the synthesis of prostaglandins and decreasing inflammation.

Aplicación

This pharmaceutical secondary standard can also be used as follows:

• Development of three spectrophotometric methods to determine meloxicam in its pharmaceutical formulations
• Voltammetric determination of meloxicam in pharmaceutical formulations using a boron-doped diamond electrode (BDDE)
• High-performance liquid chromatography-based quantitative analysis of meloxicam in its different tablet formulations
• Development and validation of a reversed-phase HPLC method for the separation and estimation of meloxicam in its pharmaceutical dosage forms
• Quantification of meloxicam and piroxicam from plasma samples using a liquid chromatography method combined with UV detection

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAB7807 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H301
• Consejos de prudencia: P264 - P270 - P301 + P310 - P405 - P501
• Clasificaciones de peligro: Acute Tox. 3 Oral
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable