M2772

Menthol

99%

• Sinónimos: 2-Isopropyl-5-methylcyclohexanol, Hexahydrothymol
• Fórmula empírica (notación de Hill): C₁₀H₂₀O
• Número de CAS: 89-78-1
• Peso molecular: 156.27
• Beilstein: 3194263
• Número CE: 201-939-0
• Número MDL: MFCD00001484
• Código UNSPSC: 12352212
• ID de la sustancia en PubChem: 24896764
• NACRES: NA.25

Propiedades

• presión de vapor: 0.8 mmHg ( 20 °C)
• Nivel de calidad: 200
• Ensayo: 99%
• bp: 216 °C (lit.)
• mp: 34-36 °C (lit.)
• densidad: 0.89 g/mL at 25 °C (lit.)
• aplicaciones: metabolomics; vitamins, nutraceuticals, and natural products
• cadena SMILES: CC(C)C1CCC(C)CC1O
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3
• Clave InChI: NOOLISFMXDJSKH-UHFFFAOYSA-N
• Información sobre el gen: human ... TRPA1(8989) , TRPM8(79054)

Descripción

Descripción general

Menthol (C₁₀H₂₀O) is a terpenoid compound. It is extracted from the plants belonging to Mentha genus in the Lamiaceae family.

Menthol is a cyclic monoterpene alcohol, which is extracted from essential oils of Mentha canadensis and Mentha x piperita. It possesses antimicrobial, anticancer and anti-inflammatory properties. Menthol acts as a transient receptor potential cation channel (TRPM8) agonist. It also exhibits analgesic, antipruritic, anesthetic and cooling effects.

Aplicación

Menthol has been used:

• to test its antifungal susceptibility
• to determine its efficacy as an anesthetic in fish
• to activate transient receptor potential cation channel (TRPM8)
• as an odorant for measuring sniffing dynamics

Acciones bioquímicas o fisiológicas

Menthol exhibits antifungal action on the membrane permeability and the cell wall consistency, this might leads to cell death or inhibition of the C. albicans filamentation. Therefore, it can be used as a potential therapeutic agent for candidiasis. In addition to antifungal activity, menthol also exhibits anesthetic, antispasmodic, anti-ulcer and antiviral properties. It is considered as a safe compound for animal life. Therefore, Menthol is widely used in pharmaceuticals, cosmetics and food industries.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319
• Consejos de prudencia: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 204.8 °F
• Punto de inflamabilidad (°C): 96 °C
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves