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Merck

E4009

Sigma-Aldrich

Eosin Y

Dye content ~99%, Powder

Sinónimos:

2′,4′,5′,7′-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43

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About This Item

Fórmula empírica (notación de Hill):
C20H8Br4O5
Número de CAS:
Peso molecular:
647.89
Colour Index Number:
45380:2
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Eosin Y, Dye content ~99 %

form

powder

Quality Level

composition

Dye content, ~99%

color

light red to red/pink

solubility

ethanol: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5ccccc45)c1Br

InChI

1S/C20H8Br4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H

InChI key

DBZJJPROPLPMSN-UHFFFAOYSA-N

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Application

Eosin Y has been used as a stain:
  • to determine the location of the brain sections
  • for staining of fixed liver tissue
  • for histological examination of brain sections from the dorsal hippocampus

Biochem/physiol Actions

Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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An immunohistochemical analysis of SERT in the blood-brain barrier of the male rat brain.
Young LW, et al.
Histochemistry and Cell Biology, 144, 321-321 (2015)
Antonello Mai et al.
Journal of medicinal chemistry, 51(7), 2279-2290 (2008-03-20)
A number of new compounds bearing two ortho-bromo- and ortho, ortho-dibromophenol moieties linked through a saturated/unsaturated, linear/(poly)cyclic spacer (compounds 1- 9) were prepared as simplified analogues of AMI-5 (eosin), a recently reported inhibitor of both protein arginine and histone lysine
Florian Ménard et al.
Bioorganic & medicinal chemistry, 17(22), 7647-7657 (2009-10-13)
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Sun J, et al.
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Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.
Gao Z, et al.
The Journal of Biological Chemistry, 284, 18368-18368 (2009)

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