AB2233
Anti-Galanin Antibody
serum, from rabbit
Sinónimos:
galanin prepropeptide, galanin-message-associated peptide, galanin-related peptide
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
serum
tipo de anticuerpo
primary antibodies
clon
polyclonal
reactividad de especies
rat
reactividad de especies (predicha por homología)
mouse, boar, human
técnicas
immunohistochemistry: suitable (paraffin)
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
wet ice
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... GAL(51083)
Descripción general
Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.
Especificidad
Cat. # AB2233 recognizes Galanin
Reactivity with other species has not been determined.
Inmunógeno
Synthetic Linear Peptide
Aplicación
Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
Calidad
Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.
Descripción de destino
13.3 kDa
Forma física
Serum with 0.05% NaN3
Almacenamiento y estabilidad
Maintain at -20°C for up to 1 year from date of receipt.
Nota de análisis
Control
Rat Cerebellum Tissue
Rat Cerebellum Tissue
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Yutaro Komuro et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(42), 8725-8741 (2021-09-01)
Galanin, one of the most inducible neuropeptides, is widely present in developing brains, and its expression is altered by pathologic events (e.g., epilepsy, ischemia, and axotomy). The roles of galanin in brain development under both normal and pathologic conditions have
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