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Key Documents

AB5909

Sigma-Aldrich

Anti-Galanin Antibody

serum, Chemicon®

Sinónimos:

Anti-ETL8, Anti-GAL-GMAP, Anti-GALN, Anti-GLNN, Anti-GMAP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GALR1(2587)

Specificity

Recognizes human Galanin. It is expected that the antibody will cross react with rat and mouse and other species due to the fact that galanin is extremely conserved.

Immunogen

Synthetic peptide from human Galanin. The immunogen peptide is available for use in absorbtion studies (Catalog Number AG370).

Application

Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

CNS Control of Metabolism
This Anti-Galanin Antibody is validated for use in ELISA, IH for the detection of Galanin.
Western blot: 1:1000-1:5000 using ECL

Immunohistochemistry

ELISA: 1:10,000-1:100,000 using 50-100 ng/well control peptide (Catalog Number AG370) per well.

Optimal working dilutions must be determined by the end user.

Target description

The unprocessed precursor is 13.3 kDa, the mature form is 3.16 kDa

Linkage

Replaces: AB1985

Physical form

Rabbit serum. Liquid with 0.05% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


Certificados de análisis (COA)

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Eunmi Kim et al.
Scientific reports, 9(1), 5025-5025 (2019-03-25)
Spexin (SPX) is a highly conserved neuropeptide that is widely expressed in mammalian brain and peripheral tissue. In teleost, SPX1 is mainly expressed in the brain and ovary, and is involved in reproduction and food intake. A second form of
Laura Corradi et al.
Current biology : CB, 32(7), 1497-1510 (2022-02-28)
Animals possess neuronal circuits inducing stress to avoid or cope with threats present in their surroundings, for instance, by promoting behaviors, such as avoidance and escape. However, mechanisms must exist to tightly control responses to stressors, since overactivation of stress
Megan B Miller et al.
Journal of neurochemistry, 140(6), 889-902 (2016-07-29)
Kalirin (Kal), a dual Rho GDP/GTP exchange factor (GEF), plays essential roles within and outside the nervous system. Tissue-specific, developmentally regulated alternative splicing generates isoforms with one (Kal7) or two (Kal9, Kal12) GEF domains along with a kinase (Kal12) domain;
Sabine Reichert et al.
Neuron, 104(2), 370-384 (2019-09-21)
Sleep pressure increases during wake and dissipates during sleep, but the molecules and neurons that measure homeostatic sleep pressure remain poorly understood. We present a pharmacological assay in larval zebrafish that generates short-term increases in wakefulness followed by sustained rebound
Paweł Janikiewicz et al.
International journal of molecular sciences, 22(24) (2021-12-25)
Although guanethidine (GUA) was used in the past as a drug to suppress hyperactivity of the sympathetic nerve fibers, there are no available data concerning the possible action of this substance on the sensory component of the peripheral nervous system

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