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Key Documents

8.52036

Sigma-Aldrich

Fmoc-Hyp(tBu)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem®

Sinónimos:

Fmoc-Hyp(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-trans-4-hydroxyproline

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About This Item

Fórmula empírica (notación de Hill):
C24H27NO5
Número de CAS:
Peso molecular:
409.47
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22

product name

Fmoc-Hyp(tBu)-OH, Novabiochem®

Quality Level

product line

Novabiochem®

assay

≥95.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

63 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

15-25°C

InChI

1S/C24H27NO5/c1-24(2,3)30-15-12-21(22(26)27)25(13-15)23(28)29-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,27)/t15-,21+/m1/s1

InChI key

WPBXBYOKQUEIDW-VFNWGFHPSA-N

General description

Standard building block for introduction of hydroxyproline amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Application

  • Rational design of plant hairpin-like peptide EcAMP1: Structural–functional correlations to reveal antibacterial and antifungal activity: Discusses the use of Fmoc-Hyp(tBu)-OH in designing peptides that exhibit significant antibacterial and antifungal properties (Barashkova et al., 2022).

Linkage

Replaces: 04-12-1078

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.50 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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