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M-020

Supelco

S(+)-Methamphetamine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

dextro-Methamphetamine

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About This Item

Fórmula empírica (notación de Hill):
C10H15N
Número de CAS:
537-46-2
Peso molecular:
149.23
MDL number:
MFCD00079140
UNSPSC Code:
41116107
PubChem Substance ID:
329817739
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

CN[C@@H](C)Cc1ccccc1

InChI

1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1

Inchi Key

MYWUZJCMWCOHBA-VIFPVBQESA-N

Gene Information

human ... SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)

General description

Methamphetamine is a psychostimulant drug of the phenethylamine and amphetamine classes. Known by the street names "meth," "ice," and "glass", this Snap-N-Spike® reference solution is applicable for use in LC/MS or GC/MS applications including clinical toxicology, sports testing, forensic analysis, or urine drug testing. The dextrorotatory isomer of methamphetamine is sold under the trade name Desoxyn® for treatment of ADHD and obesity.

Application


  • Pharmacokinetic Studies of S(+)-Methamphetamine: A comprehensive study assessing the pharmacokinetic profile of S(+)-Methamphetamine highlighted its rapid absorption and metabolism, offering critical insights into its therapeutic potential and challenges in drug abuse scenarios. This research aids in optimizing dosing regimens and understanding the drug′s behavior in biological systems, essential for both clinical applications and forensic investigations (Rushton et al., 2024).

  • Pharmaceutical Applications of S(+)-Methamphetamine: Research on S(+)-Methamphetamine′s role in neurochemical processes explored its effects on neurotransmitter systems, particularly focusing on its potential therapeutic applications for attention deficit hyperactivity disorder (ADHD) and weight loss. Studies like these inform drug design and repurposing strategies, helping to mitigate abuse risks while harnessing pharmacological benefits (Pardo et al., 2024).

  • Drug Metabolism and Enantiomeric Analysis: Investigations into the metabolism of S(+)-Methamphetamine have provided detailed insights into its biotransformation pathways, crucial for developing antidotes and treatment strategies for overdose cases. This research also enhances the understanding of enantiomeric differences in drug activity, supporting the development of more targeted and effective therapeutic agents (Liut et al., 2024).

  • Clinical Trials and Neurological Research: Systematic reviews of clinical trials involving S(+)-Methamphetamine have elucidated its complex pharmacodynamics and associated behavioral effects. This information is vital for neuroscientists and pharmacologists working to develop safer and more effective CNS stimulants with fewer side effects and lower abuse potential (Barkholtz et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Desoxyn is a registered trademark of Abbott Laboratories Corp.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Related product

Referencia del producto
Descripción
Precios

M-023

(±)-Methamphetamine-D5 solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-090

(±)-Methamphetamine-D9 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-091

(±)-Methamphetamine-D9 solution, 1 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

A-050

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M-025

Methamphetamine/Cocaine/Heroin solution, 250 μg/mL each component in acetonitrile, ampule of 1.0 mL, certified reference material, Cerilliant®

M-004

(±)-Methamphetamine-D5 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-009

(±)-Methamphetamine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-016

(±)-Methamphetamine-D8 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-022

(±)-Methamphetamine solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-024

R(-)-Methamphetamine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-034

(±)-Methamphetamine-D8 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-059

(±)-Methamphetamine-D11 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-060

(±)-Methamphetamine-D11 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-092

(±)-Methamphetamine-D14 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-093

(±)-Methamphetamine-D14 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

M-259

(±)-Methamphetamine-13C6 hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant®

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

New Meth vaccine shows promise in animals.
Human vaccines & immunotherapeutics, 9(1), 9-10 (2013-04-10)
Diane M Herbeck et al.
Journal of psychoactive drugs, 45(2), 132-140 (2013-08-03)
This study examines health and legal problems associated with use of commonly reported substances and combinations of substances in a sample of adults with long histories of methamphetamine (meth) use. Data are from a 2009-11 eight-year follow-up interview in an
Adam Kelly
Emergency medicine journal : EMJ, 30(4), 339-340 (2013-03-21)
A short-cut review was carried out to establish which clinical parameters are useful in predicting outcome in patients who present having body packed metamphetamine. Eleven papers were found using the reported searches, of which one presented the best evidence to
Glenn-Milo Santos et al.
Journal of acquired immune deficiency syndromes (1999), 63(4), 540-544 (2013-04-11)
We evaluated the relationship between frequency and number of substances used and HIV risk [ie, serodiscordant unprotected anal intercourse (SDUAI)] among 3173 HIV-negative substance-using MSM. Compared with nonusers, the adjusted odds ratio (AOR) for SDUAI among episodic and at least
Dental ethics case 25: the drug-abusing patient--what are my ethical obligations to treat?
S Naidoo
SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 67(8), 474-475 (2013-08-21)
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Protocolos

Accurate Biological Testing for Amphetamine and Methamphetamine Abuse Using Chiral HPLC and MS Detection

Optimized sample prep and chiral chromatography methods for the LC/MS analysis of these drug enantiomers in urine

Biological Testing for Amphetamine and Methamphetamine Abuse

In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.

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