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Merck

B-004

Supelco

Benzoylecgonine solution

Benzoylecgonine solution
1 of 1 reviewers received a sample product or took part in a promotion

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C16H19NO4
Número de CAS:
Peso molecular:
289.33
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

certified reference material

Nivel de calidad

Formulario

liquid

Características

SNAP-N-SPIKE®, SNAP-N-SHOOT®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

forensics and toxicology

Formato

single component solution

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

cadena SMILES

CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)c3ccccc3)C(O)=O

InChI

1S/C16H19NO4/c1-17-11-7-8-12(17)14(15(18)19)13(9-11)21-16(20)10-5-3-2-4-6-10/h2-6,11-14H,7-9H2,1H3,(H,18,19)/t11-,12+,13-,14+/m0/s1

Clave InChI

GVGYEFKIHJTNQZ-RFQIPJPRSA-N

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Descripción general

This certified reference standard is suitable for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to urine drug testing.

Benzoylecgonine is the primary metabolite of cocaine and a major biomarker for the determination of cocaine use. Benzoylecgonine is also the main pharmaceutical ingredient in the prescription drug Esterom, a topical analgesic used for the relief of muscle pain.

Aplicación

The certified reference solution (CRM) in solution can also be used as follows:
  • Development and validation of a high-performance liquid chromatography-diode array detector (HPLC-DAD) based method to determine cocaine, its two main degradation products, and the common adulterants found in cocaine-based products from 115 seized samples
  • Analysis of benzoylecgonine in human urine samples using a monolithic molecularly imprinted polymer (MIP) for the solid phase microextraction (SPME) followed by UV detection[1]
  • Separation and determination of cocaine and its metabolites― benzoylecgonine, ecgonine methyl ester, and cocaethylene in hair samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS)[2]
  • Estimation of cocaine, benzoylecgonine, cocaethylene, ecgonine methyl ester (EME), and norcocaine in dried blood spots (DBS) by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • Multi-residue analysis of xylazine, free morphine, 6-acetylmorphine, codeine, cocaine, and benzoylecgonine in post-mortem blood samples by ultra-high-pressure liquid chromatography-electrospray ionization (UPLC-ESI) and triple-quadrupole tandem mass spectrometry[3]

Características y beneficios

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Producto relacionado

Referencia del producto
Descripción
Precios

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup


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Certificados de análisis (COA)

Lot/Batch Number

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Thomas Bouvarel et al.
Talanta, 233, 122611-122611 (2021-07-04)
A simple, selective, and sensitive method involving a miniaturized solid phase extraction step based on a monolithic molecularly imprinted polymer (MIP) directly coupled on-line to UV detection was developed for the determination of benzoylecgonine (BZE) in complex biological samples. Monolithic
Charles A Dackis et al.
Journal of substance abuse treatment, 43(3), 303-312 (2012-03-02)
This is a randomized, double-blind, placebo-controlled study of modafinil treatment for cocaine dependence. Patients (N = 210) who were actively using cocaine at baseline were randomized to 8 weeks of modafinil (0 mg/day, 200 mg/day, or 400 mg/day) combined with
Nadine Schaefer et al.
Analytical and bioanalytical chemistry, 405(1), 247-258 (2012-10-19)
In the context of driving ability diagnostics in Germany, administrative cutoffs for various drugs and pharmaceuticals in urine have been established. Two liquid chromatography-tandem mass spectrometry methods for simultaneous detection and quantification of amphetamines, designer amphetamines, benzoylecgonine, benzodiazepines, opiates, and
Sara Castiglioni et al.
Environmental science & technology, 47(3), 1452-1460 (2012-12-25)
The aim of this study was to integrally address the uncertainty associated with all the steps used to estimate community drug consumption through the chemical analysis of sewage biomarkers of illicit drugs. Uncertainty has been evaluated for sampling, chemical analysis
N Nikolettos et al.
Clinical and experimental obstetrics & gynecology, 39(1), 36-42 (2012-06-09)
To investigate the response of pregnant and non pregnant rat myometrium to benzoylecgonine, a cocaine metabolite, and oxytocin and to investigate the efficiency of ritodrine and atosiban to overcome the effects of benzoylecgonine and oxytocin. Isolation of rat myometrial tissue

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Analysis of 20 pharmaceutical compounds in calf serum using Supel™ Swift HLB SPE cartridge for cleanup and LC-MS determination and another commercially available HLB cartridge for comparison.

Analysis of 20 pharmaceutical compounds in calf serum using Supel™ Swift HLB SPE cartridge for cleanup and LC-MS determination and another commercially available HLB cartridge for comparison.

Analysis of 20 pharmaceutical compounds in calf serum using Supel™ Swift HLB SPE cartridge for cleanup and LC-MS determination and another commercially available HLB cartridge for comparison.

Analysis of 20 pharmaceutical compounds in calf serum using Supel™ Swift HLB SPE cartridge for cleanup and LC-MS determination and another commercially available HLB cartridge for comparison.

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