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Merck

850368C

Avanti

20:0 PC

1,2-diarachidoyl-sn-glycero-3-phosphocholine, chloroform

Sinónimos:

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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About This Item

Fórmula empírica (notación de Hill):
C48H96NO8P
Número de CAS:
Peso molecular:
846.25
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850368C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850368C

concentration

10 mg/mL (850368C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

InChI key

YKIOPDIXYAUOFN-YACUFSJGSA-N

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
The mucosal layer of the colon has phosphatidylcholine (PC) as a vital constituent.

Application

20:0 PC has been used in collision cross section (CCS) calibration mixture for lipid identification.
It may be used:
  • as a component in giant unilamellar vesicles (GUVs) for a two-photon fluorescence microscopy study
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization
  • as a component in giant unilamellar vesicles (GUVs) to study its interaction with Crotalus atrox-secreted phospholipase A2 (sPLA2)

Biochem/physiol Actions

Phosphatidylcholine (PC) may participate in the signaling of neuronal differentiation. It can serve as a surfactant to block the penetrance of bacteria by generating a hydrophobic surface.

Packaging

5 mL Clear Glass Sealed Ampule (850368C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

The Use of LipidIMMS Analyzer for Lipid Identification in Ion Mobility-Mass Spectrometry-Based Untargeted Lipidomics
Ion Mobility-Mass Spectrometry, 269-282 (2020)
Susana A Sanchez et al.
Biophysical journal, 82(4), 2232-2243 (2002-03-28)
We describe the interaction of Crotalus atrox-secreted phospholipase A2 (sPLA2) with giant unilamellar vesicles (GUVs) composed of single and binary phospholipid mixtures visualized through two-photon excitation fluorescent microscopy. The GUV lipid compositions that we examined included 1-palmitoyl-2-oleoyl-phosphatidylcholine, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and
Devaki A Kelkar et al.
Biochimica et biophysica acta, 1768(5), 1103-1113 (2007-02-27)
The matching of hydrophobic lengths of integral membrane proteins and the surrounding lipid bilayer is an important factor that influences both structure and function of integral membrane proteins. The ion channel gramicidin is known to be uniquely sensitive to membrane
L A Bagatolli et al.
Biophysical journal, 79(1), 434-447 (2000-06-27)
Giant unilamellar vesicles (GUVs) composed of different phospholipid binary mixtures were studied at different temperatures, by a method combining the sectioning capability of the two-photon excitation fluorescence microscope and the partition and spectral properties of 6-dodecanoyl-2-dimethylamino-naphthalene (Laurdan) and Lissamine rhodamine
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)

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