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913375

Sigma-Aldrich

Branched polyethylenimine solution

2mg/mL aqueous solution, suitable for biomedical research

Sinónimos:

PEI solution

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About This Item

Fórmula lineal:
H(NHCH2CH2)mNH2
Número de CAS:
9002-98-6
UNSPSC Code:
12352116
NACRES:
NA.23

Quality Level

100

form

liquid

concentration

2 mg/mL

color

colorless to pale yellow

storage temp.

2-8°C

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

InChI key

NOWKCMXCCJGMRR-UHFFFAOYSA-N

Categorías relacionadas

Application

High molecular weight branched PEI is commonly used in gene delivery due to its high transfection efficiency in a broad range of cells. Branched PEI has been used to successfully deliver genetic material both in vitro and in vivo, while maintaining low cytotoxicity with DNA complexation.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

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Certificados de análisis (COA)

Lot/Batch Number
MKCT6591
MKCM5054

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O Boussif et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(16), 7297-7301 (1995-08-01)
Several polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyamidoamine polymers, are efficient transfection agents per se--i.e., without the addition of cell targeting or membrane-disruption agents. This observation led us to test the cationic polymer polyethylenimine
W T Godbey et al.
Journal of biomedical materials research, 45(3), 268-275 (1999-07-09)
Poly(ethylenimine) (PEI) samples of various molecular weights and pHs were used to transfect endothelial cells to achieve levels of gene expression for comparison. PEIs with nominal molecular weights of 600, 1200, 1800, 10,000, and 70,000 Da were examined at pHs

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CRISPR/Cas9 delivery via nonviral nanoparticles shows promising advancements for gene editing in disease treatment.

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CRISPR/Cas9 delivery via nonviral nanoparticles shows promising advancements for gene editing in disease treatment.

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