689440
O-(2-Azidoethyl)heptaethylene glycol
≥95% (oligomer purity)
Sinónimos:
Azido-PEG (n=7)
About This Item
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Quality Level
assay
≥95% (oligomer purity)
form
powder
mol wt
average Mn 400
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
Ω-end
hydroxyl
α-end
azide
functional group
azide
hydroxyl
storage temp.
2-8°C
SMILES string
OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
InChI
1S/C16H33N3O8/c17-19-18-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-20/h20H,1-16H2
InChI key
BUMODEBRFGPXRM-UHFFFAOYSA-N
Application
Some of the reported applications include:
- Synthesis of strain-stiffening hydrogels through self-assembly of oligomers fibres derived from Azido-PEG (n=7).
- Synthesis of biodegradable tetra-PEG hydrogels for drug delivery system.
- Synthesis of heterobifunctional oligo(ethylene glycol) linkers for bioconjugation and targeted drug delivery.
- Preparation of synthetic amphiphiles for programmed pH-dependent dispersions of carbon nanotubes (CNTs).
- Selective glycoprotein detection through allosteric click-imprinting by using a self-assembled monolayer developed from the above oligomer.
- Preparation of bioactivated quantum dot micelles containing fluorescent nanocrystals.
Packaging
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Artículos
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.
Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.
Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.
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