460923

Propargyl chloroformate

96%

• Sinónimos: (Prop-2-ynyloxy)carbonyl chloride, 2-Propyn-1-yl carbonochloridate, 2-Propynyl chloroformate, Prop-2-yn-1-yl carbonochloridate, Propargyloxycarbonyl chloride
• Fórmula lineal: HC≡CCH₂OCOCl
• Número de CAS: 35718-08-2
• Peso molecular: 118.52
• Beilstein/REAXYS Number: 1745399
• MDL number: MFCD00270127
• UNSPSC Code: 12352100
• PubChem Substance ID: 24869771
• NACRES: NA.22

Propiedades

• vapor pressure: 0.65 psi ( 20 °C)
• Quality Level: 100
• assay: 96%
• reaction suitability: reaction type: click chemistry
• refractive index: n20/D 1.435 (lit.)
• bp: 118-122 °C (lit.)
• density: 1.215 g/mL at 25 °C (lit.)
• functional group: chloro
• storage temp.: 2-8°C
• SMILES string: ClC(=O)OCC#C
• InChI: 1S/C4H3ClO2/c1-2-3-7-4(5)6/h1H,3H2
• InChI key: RAMTXCRMKBFPRG-UHFFFAOYSA-N

Descripción

General description

Propargyl chloroformate is a propargyl ester. It serves as a protecting group for the hydroxy and amino functional group. Rates of solvolysis of propargyl chloroformate has been analyzed in various solvents of widely varying nucleophilicity and ionizing power values using the extended Grunwald-Winstein equation.

Application

Propargyl chloroformate may be used for the preparation of the following:

• binaphthol-diacetylene derivatives
• propargyl pentafluorophenyl carbonate
• N-Poc protected amino acids (Poc = propargyloxycarbonyl)

Información de seguridad

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• hcodes: H226,H302,H311 + H331,H314
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 86.0 °F - closed cup
• flash_point_c: 30 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter