419362

Di-tert-butyl N,N-diisopropylphosphoramidite

95%

• Sinónimos: Di-tert-butyl diisopropylphosphoramidite
• Fórmula lineal: [(CH₃)₂CH]₂NP[OC(CH₃)₃]₂
• Número de CAS: 137348-86-8
• Peso molecular: 277.38
• Beilstein/REAXYS Number: 4858847
• MDL number: MFCD00153506
• UNSPSC Code: 12352001
• PubChem Substance ID: 24866105
• NACRES: NA.22

Propiedades

• Quality Level: 200
• assay: 95%
• form: liquid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• refractive index: n20/D 1.444 (lit.)
• bp: 85-90 °C/0.2 mmHg (lit.)
• density: 0.879 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CC(C)N(C(C)C)P(OC(C)(C)C)OC(C)(C)C
• InChI: 1S/C14H32NO2P/c1-11(2)15(12(3)4)18(16-13(5,6)7)17-14(8,9)10/h11-12H,1-10H3
• InChI key: YGFLCNPXEPDANQ-UHFFFAOYSA-N

Descripción

Application

Di-tert-butyl N,N-diisopropylphosphoramidite is a general reagent to introduce tert-butyl-protected phosphate groups. It is commonly used in phosphorylation of biomolecules. It can also be used in the synthesis of phosphoramidate-linked glycoconjugates.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter