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296783

Sigma-Aldrich

5-Benzimidazolecarboxylic acid

96%

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About This Item

Fórmula empírica (notación de Hill):
C8H6N2O2
Número de CAS:
15788-16-6
Peso molecular:
162.15
MDL number:
MFCD00011555
UNSPSC Code:
12352100
eCl@ss:
32151902
PubChem Substance ID:
24857875
NACRES:
NA.22

assay

96%

mp

>300 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc2[nH]cnc2c1

InChI

1S/C8H6N2O2/c11-8(12)5-1-2-6-7(3-5)10-4-9-6/h1-4H,(H,9,10)(H,11,12)

InChI key

COYPLDIXZODDDL-UHFFFAOYSA-N

General description

Drug-specific monoclonal antibodies were produced against the very small drug hapten, 5-benzimidazolecarboxylic acid.

Application

5-Benzimidazolecarboxylic acid has been used in the preparation of:
  • 1H-benzoimidazole-5-carboxylic acid benzotriazol-1-yl ester
  • piperidin-1-yl(1-m-tolyl-1H-benzo[d]imidazol-5-yl)methanone

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

171778

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E S Medlock et al.
The Anatomical record, 207(1), 31-41 (1983-09-01)
Mouse fetal liver was studied ultrastructurally to identify and characterize the developing hepatic parenchyma or prehepatocyte which may be responsible for producing the liver hemopoietic environment. It was observed that as the liver develops, there is close association of endodermal
Ajit Jadhav et al.
Probe Reports from the NIH Molecular Libraries Program, 2010 Mar 4 (Updated 2011 Mar 11) (2011-07-08)
15-hydroxyprostaglandin dehydrogenase (15-PGDH; HPGD) is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation. The anabolic pathways of prostaglandins are well-characterized, especially with respect to regulation of the cyclooxygenase (COX) enzymes. In
E Moran et al.
Journal of immunological methods, 271(1-2), 65-75 (2002-11-26)
Drug-specific monoclonal antibodies (MAbs) were produced against the very small drug hapten (162.15 Da), 5-benzimidazolecarboxylic acid, an analogue of 2-(4-Thiazolyl)benzimidazole (TBZ) but lacking the thiol group. TBZ is widely used as a broad-spectrum anthelmintic in various animal species and humans
Xiaofei Chen et al.
Biomaterials science, 3(6), 870-878 (2015-07-30)
Herein, hyperbranched poly(ethylene glycol)-based supramolecular nanoparticles with pH-sensitive properties were designed and used for targeted drug delivery. Via host-guest recognition between benzimidazole anchored poly(ethylene glycol)-hyperbranched polyglycerol (PEG-HPG-BM) and folic acid modified CD (FA-CD), targeted supramolecular nanoparticles (TSNs) were fabricated. At

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