234524

O-Phenyl chlorothionoformate

99%

• Sinónimos: Phenyl thionochloroformate
• Fórmula lineal: ClC(S)OC₆H₅
• Número de CAS: 1005-56-7
• Peso molecular: 172.63
• Beilstein/REAXYS Number: 774830
• EC Number: 213-736-4
• MDL number: MFCD00004920
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854046
• NACRES: NA.22

Propiedades

• Quality Level: 200
• assay: 99%
• form: liquid
• refractive index: n20/D 1.581 (lit.)
• bp: 81-83 °C/6 mmHg (lit.)
• density: 1.248 g/mL at 25 °C (lit.)
• functional group: chloro; phenoxy
• SMILES string: ClC(=S)Oc1ccccc1
• InChI: 1S/C7H5ClOS/c8-7(10)9-6-4-2-1-3-5-6/h1-5H
• Inchi Key: KOSYAAIZOGNATQ-UHFFFAOYSA-N

Descripción

Application

O-Phenyl chlorothionoformate has been used in:

• stereodirected synthesis of optically active, (−)-mintlactone
• synthesis of peptide α-thioesters having a variety of C-terminal amino acids
• synthesis of scyllo-inositol derivatives
• thionocarbonylation of unprotected thymine nucleosides
• preparation of phenoxythiocarbonyl esters of protected ribonucleosides

Información de seguridad

• Pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 177.8 °F - closed cup
• flash_point_c: 81 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter