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1096779

USP

Casticin

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

3′,5-Dihydroxy-3,4′,6,7-tetramethoxyflavone, 3,4′,6,7-Tetra-O-methylquercetagetin, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7-trimethoxychromen-4-one, Quercetagetin 3,4′,6,7-tetramethyl ether, Vitexicarpin

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About This Item

Fórmula empírica (notación de Hill):
C19H18O8
Número de CAS:
479-91-4
Peso molecular:
374.34
Beilstein/REAXYS Number:
1300392
MDL number:
MFCD00210481
UNSPSC Code:
41116107
PubChem Substance ID:
329749248
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

casticin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(cc1O)C2=C(OC)C(=O)c3c(O)c(OC)c(OC)cc3O2

InChI

1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3

InChI key

PJQLSMYMOKWUJG-UHFFFAOYSA-N

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General description

Casticin is a flavonoid, widely used as an anti-inflammatory agent. It has anti-tumor properties and is considered to be a potent immunomodulatory and cytotoxic compound.

Application

It was may be used as reference standard to compare retention time and ion peaks in plant extracts during GC/MS analysis to quantify Casticin and artemetin.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Jia-Kun Shen et al.
Annals of hematology, 88(8), 743-752 (2009-01-14)
Casticin, a component from Vitex rotundifolia, widely used as an anti-inflammatory agent in Chinese traditional medicine, was reported to have anti-tumor activities. This study aims to examine the anti-leukemic activity of casticin on leukemia cells and its molecular mechanism. Cell
Pamela J Weathers et al.
Planta medica, 78(10), 1024-1026 (2012-06-08)
A number of flavonoids including casticin and artemetin from Artemisia annua have shown synergism with artemisinin against Plasmodium falciparum, but it is unclear if the flavonoids are also extracted into a tea infusion of the plant. Using a tea infusion
M Ahmed Mesaik et al.
Phytotherapy research : PTR, 23(11), 1516-1520 (2009-05-15)
Casticin (1), a flavonoid isolated from the aerial parts of Vitex agnus-castus, was found to be a potent immunomodulatory and cytotoxic compound. The activity was tested in vitro for chemiluminescence, chemotaxis, T-cell proliferation and cytotoxicity. Casticin (1) exhibited a significant

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