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Merck

U4883

Supelco

Urea

8 M (after reconstitution with 16 mL high purity water)

Sinónimos:

Urea solution, Carbamide, Carbonyldiamide

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About This Item

Fórmula lineal:
NH2CONH2
Número de CAS:
Peso molecular:
60.06
Beilstein/REAXYS Number:
635724
EC Number:
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.25

form

powder

concentration

8 M (after reconstitution with 16 mL high purity water)

solubility

H2O: soluble (1 vial plus 16 mL)

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

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General description

Urea is a chaotropic agent and is used for protein denaturation. It disturbs the hydrogen bonds in the secondary, tertiary and quaternary structure of proteins. It can also disturb hydrogen bonding present in DNA secondary structure.

Application

Useful for solubilizing and denaturing proteins in preparation for 2D-PAGE, enzymatic digests, IMAC Chromatography, and related procedures.
Urea has been used for protein sample preparation for reverse-phase nanospray liquid chromatography-tandem mass spectrometry.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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