T8019

Tentoxin from Alternaria tenuis

Naturally occurring phytotoxic cyclic tetrapeptide

• Fórmula empírica (notación de Hill): C₂₂H₃₀N₄O₄
• Número de CAS: 28540-82-1
• Peso molecular: 414.50
• Número MDL: MFCD00133844
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24900492
• NACRES: NA.56

Propiedades

• origen biológico: fungus (Alternaria tenuis)
• Nivel de calidad: 200
• Ensayo: ≥95% (HPLC)
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CC(C)CC1NC(=O)C(C)N(C)C(=O)CNC(=O)\C(=C/c2ccccc2)N(C)C1=O
• InChI: 1S/C22H30N4O4/c1-14(2)11-17-22(30)26(5)18(12-16-9-7-6-8-10-16)21(29)23-13-19(27)25(4)15(3)20(28)24-17/h6-10,12,14-15,17H,11,13H2,1-5H3,(H,23,29)(H,24,28)/b18-12-/t15-,17-/m0/s1
• Clave InChI: SIIRBDOFKDACOK-LFXZBHHUSA-N

Descripción

Descripción general

Tentoxin is a majorly occurring cyclic tetrapeptide mycotoxin that is excreted by the Alternaria fungal species like Alternaria alternata and Alternaria tenuis.[1]

Acciones bioquímicas o fisiológicas

It induces chlorosis in germinating seedlings of many dicotyledonous plants. Tentoxin has been postulated to inhibit cyclic photophosphorylation by acting as an energy transfer inhibitor at the terminal steps of ATP synthesis and to target the F1 moiety of photosynthetic H⁺-ATPases. A kinetic analysis of the action of tentoxin on the chloroplast F1 H⁺-ATPase (CF1) portion of chloroplast ATP synthase has been reported.

Tentoxin is phytotoxic, which induces chlorosis in plant leaves and germinating seedlings.[2] It also halts photophosphorylation[1] by inhibiting chloroplastic ATP synthase.[2] Tentoxin over energizes thylakoids and is converted to isotentoxin by UV irradiation.[3]

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)