SML0556

LY344864 hydrochloride

≥98% (HPLC)

• Sinónimos: N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-benzamide hydrochloride
• Fórmula empírica (notación de Hill): C₂₁H₂₂FN₃O · HCl
• Número de CAS: 1217756-94-9
• Peso molecular: 387.88
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 10 mg/mL, clear
• storage temp.: 2-8°C
• InChI: 1S/C21H22FN3O.ClH/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13;/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26);1H/t16-;/m1./s1
• InChI key: OKUHLSYESBLBCP-PKLMIRHRSA-N

Descripción

Biochem/physiol Actions

LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. It has an EC₅₀ of 3 nM, and displays > 80-fold selectivity over other 5-HT receptors

LY344864 might be useful in the treatment approach for migraine. LY344864 is found to prevent the extravasation of dura protein and reduce c-fos like immunoreactions induced by capsaicin.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable