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SMB00119

Sigma-Aldrich

Arjunolic acid

≥95% (LC/MS-ELSD)

Sinónimos:

2,3,23-Trihydroxyolean-12-en-28-oic acid

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About This Item

Fórmula empírica (notación de Hill):
C30H48O5
Número de CAS:
465-00-9
Peso molecular:
488.70
Número MDL:
MFCD11113458
Código UNSPSC:
12352205
ID de la sustancia en PubChem:
329824797
NACRES:
NA.25

Nivel de calidad

200

Ensayo

≥95% (LC/MS-ELSD)

Formulario

solid

aplicaciones

metabolomics
vitamins, nutraceuticals, and natural products

temp. de almacenamiento

−20°C

cadena SMILES

CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O

InChI

1S/C30H48O5/c1-25(2)11-13-30(24(34)35)14-12-28(5)18(19(30)15-25)7-8-22-26(3)16-20(32)23(33)27(4,17-31)21(26)9-10-29(22,28)6/h7,19-23,31-33H,8-17H2,1-6H3,(H,34,35)/t19-,20+,21+,22+,23-,26-,27-,28+,29+,30-/m0/s1

Clave InChI

RWNHLTKFBKYDOJ-DDHMHSPCSA-N

Categorías relacionadas

Descripción general

Natural product derived from plant source.

Acciones bioquímicas o fisiológicas

Arjunolic acid (AA) is a triterpenoid saponin that has known anti-oxidant activity. AA has also shown promise in against type 1 diabetes through its prevention of hyperglycemia induced activation of MAPKs, PKC, NF-kB signaling cascades. Arjunolic acid is beneficial in protecting again acetaminophen (APAP)-induced liver and hepatocyte injury.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
122228344V
122228133V
122228-133V

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Prasenjit Manna et al.
Archives of toxicology, 82(3), 137-149 (2008-01-17)
Arsenic, one of the most harmful metalloids, is ubiquitous in the environment. The present study has been carried out to investigate the protective role of a triterpenoid saponin, arjunolic acid (AA) against arsenic-induced cardiac oxidative damage. In the study, NaAsO2
Prasenjit Manna et al.
Toxicology, 257(1-2), 53-63 (2009-01-10)
Increasing evidences in both experimental and clinical studies suggest that oxidative stress is involved in the pathogenesis of diabetic tissue damage. Pancreatic beta-cell death is the cause of decreased insulin production in diabetes. Streptozotocin (STZ) is widely used to induce
Jyotirmoy Ghosh et al.
Free radical biology & medicine, 48(4), 535-553 (2009-12-09)
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug and is safe at therapeutic doses but its overdose frequently causes liver injury. In earlier studies, we demonstrated that arjunolic acid (AA) has a protective effect against chemically induced hepatotoxicity.
Prasenjit Manna et al.
Basic & clinical pharmacology & toxicology, 101(5), 333-338 (2007-10-04)
Arsenic is one of the ubiquitous environmental pollutants, which affects nearly all organ systems. The present study has been carried out to investigate the hepatoprotective role of arjunolic acid, a triterpenoid saponin, against arsenic-induced oxidative damages in murine livers. Administration
Jyotirmoy Ghosh et al.
Biochimie, 95(6), 1098-1109 (2013-02-14)
In recent years, a number of studies describing the effective therapeutic strategies of medicinal plants and their active constituents in traditional medicine have been reported. Indeed, tremendous demand for the development and implementation of these plant derived biomolecules in complementary
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