SAB4503834

Anti-phospho-SGK (pSer⁴²²) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 48 kDa
• reactividad de especies: rat, human, mouse
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: O00141
• Nº de acceso UniProt: O00141
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer422)
• Información sobre el gen: human ... SGK1(6446)

Descripción

Descripción general

The serum- and glucocorticoid-regulated kinase (Sgk1) is a member of the AGC kinase family. It is located on human chromosome 6q23.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human SGK around the phosphorylation site of Ser422.

Immunogen Range: 381-430

Acciones bioquímicas o fisiológicas

The serum- and glucocorticoid-regulated kinase (Sgk1) controls ENaC (expressed renal epithelial Na⁺ channel) by mineralocorticoids. SGK1 controls p27 phosphorylation upon the activation by mTOR-Raptor.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable