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P6777

Sigma-Aldrich

Phenelzine sulfate salt

Sinónimos:

Phenelzine hydrogen sulphate

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About This Item

Fórmula empírica (notación de Hill):
C8H12N2 · H2O4S
Número de CAS:
156-51-4
Peso molecular:
234.27
Número CE:
205-856-0
Número MDL:
MFCD00050687
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
24278646
NACRES:
NA.77

origen biológico

synthetic

Ensayo

≥98% (iodine, titration)

Formulario

powder

solubilidad

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

cadena SMILES

NNCCC1=CC=CC=C1.OS(=O)(O)=O

InChI

1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

Clave InChI

RXBKMJIPNDOHFR-UHFFFAOYSA-N

Información sobre el gen

human ... MAOA(4128) , MAOB(4129)

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Acciones bioquímicas o fisiológicas

Non-selective MAO-A/B inhibitor.

Características y beneficios

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301

Consejos de prudencia

P301 + P310

Clasificaciones de peligro

Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCK9477
BCCK4308
BCCG9192
BCBN9644V
BCBX0084

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Hwan-Suck Chung et al.
Neurochemical research, 37(10), 2117-2124 (2012-07-06)
Phenelzine is a potent monoamine oxidase inhibitor that is used in patients with depression. It is also well known that nitric oxide (NO) synthase inhibitors show preclinical antidepressant-like properties, which suggests that NO is involved in the pathogenesis of depression.
Mee-Sook Song et al.
Journal of neurochemistry, 114(5), 1405-1413 (2010-06-19)
Reactive aldehydes have been implicated in the etiology of several neurological and psychiatric disorders, and there is considerable interest in drugs to counteract the actions of these aldehydes. Increased formaldehyde (FA) and up-regulation of semicarbazide-sensitive amine oxidase, which forms FA
The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Nahla Mahgoub et al.
The Journal of neuropsychiatry and clinical neurosciences, 23(2), E24-E25 (2011-06-17)
Adeline Su-Yin Ngo et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 6(4), 431-434 (2010-07-24)
Phenelzine is an irreversible monoamine oxidase inhibitor (MAOI). Hypertensive reactions after ingestion of tyramine-rich foods such as cheese are well known. However, a review of the available medical literature found no previous reports of myocardial infarction resulting from the ingestion
Marco De Giovanni et al.
Immunity, 56(7), 1548-1560 (2023-06-07)
Cryptococcus neoformans is the leading cause of fungal meningitis and is characterized by pathogenic eosinophil accumulation in the context of type-2 inflammation. The chemoattractant receptor GPR35 is expressed by granulocytes and promotes their migration to the inflammatory mediator 5-hydroxyindoleacetic acid
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