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Merck

P5556

Sigma-Aldrich

Disolución de poloxamer 188

10%, sterile-filtered, BioReagent, suitable for insect cell culture

Sinónimos:

Nonionic copolymer surfactant

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About This Item

Número de CAS:
MDL number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.75
En este momento no podemos mostrarle ni los precios ni la disponibilidad

description

non-ionic

Quality Level

sterility

sterile-filtered

product line

BioReagent

mol wt

average mol wt 8350

concentration

10%

technique(s)

cell culture | insect: suitable

impurities

endotoxin, tested

transition temp

cloud point ≥100

HLB

29

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

General description

El Poloxamer 188 (P188) es un copolímero anfifílico no iónico. Consta de una cadena central de polioxipropileno hidróbo flanqueada en los extremos por polioxietileno hidrófilo.[1]

Application

Copolímero tensioactivo no iónico

Biochem/physiol Actions

El Poloxamer 188 (P188) provoca actividades hemorreológicas, antitrombóticas, antiinflamatorias y citoprotectoras. Restaura y estabiliza la función de barrera de las membranas. El P188 inhibe también la peroxidación lipídica, reduce la tensión superficial y la adherencia celular hidrófoba.[1][2] El P-188 presenta baja toxicidad y puede usarse en la administración de medicamentos por vía oral.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Questions

  1. How does the pH of the Poloxamer 188 solution fluctuate throughout a 24-month period?

    1 answer
    1. The pH of a solution containing Poloxamer 188 may change over time due to factors such as hydrolysis or oxidation. The pH stability of Poloxamer 188 solutions has not been conducted. However, end users are encouraged to periodically monitor the solutions to ensure their stability and efficacy.

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