L0517

Leukotriene B₄

~100 μg/mL in ethanol, ≥97%

• Sinónimos: [5S,12R]-Dihydroxy-[6Z,8E,10E,14Z]-eicosatetraenoic acid
• Fórmula empírica (notación de Hill): C₂₀H₃₂O₄
• Número de CAS: 71160-24-2
• Peso molecular: 336.47
• EC Number: 200-578-6
• MDL number: MFCD00135630
• UNSPSC Code: 12352200
• PubChem Substance ID: 24896256
• NACRES: NA.77

Propiedades

• Quality Level: 200
• assay: ≥97%
• form: liquid
• concentration: ~100 μg/mL in ethanol
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O
• InChI: 1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1
• InChI key: VNYSSYRCGWBHLG-AMOLWHMGSA-N
• Gene Information: human ... LTB4R(1241) ; rat ... Ltb4r(59264)

Descripción

Biochem/physiol Actions

Proinflammatory agent. Stimulates c-Fos and c-Jun proto-oncogene transcription in human monocytes. Stimulates chemotaxis, aggregation, and degranulation of polymorphonuclear leukocytes.

Features and Benefits

This compound is featured on the Leukotriene Receptors and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Data sheet which accompanies each product includes special handling instructions. Except where noted, method for hydrolysis of methyl esters is also described.

Información de seguridad

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 57.2 °F - closed cup
• flash_point_c: 14.0 °C - closed cup