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G3295

Sigma-Aldrich

GW0742

≥98% (HPLC)

Sinónimos:

4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid

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About This Item

Fórmula empírica (notación de Hill):
C21H17F4NO3S2
Número de CAS:
317318-84-6
Peso molecular:
471.49
Número MDL:
MFCD07369423
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
24895123
NACRES:
NA.77

Nivel de calidad

100

Ensayo

≥98% (HPLC)

Formulario

powder

color

white

mp

134.5-135.5 °C

solubilidad

DMSO: >5 mg/mL
H2O: insoluble

emisor

GlaxoSmithKline

temp. de almacenamiento

2-8°C

cadena SMILES

Cc1cc(SCc2sc(nc2C)-c3ccc(c(F)c3)C(F)(F)F)ccc1OCC(O)=O

InChI

1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)

Clave InChI

HWVNEWGKWRGSRK-UHFFFAOYSA-N

Información sobre el gen

human ... PPARA(5465) , PPARD(5467) , PPARG(5468)

Acciones bioquímicas o fisiológicas

GW0742 is a highly selective PPARδ agonist. EC50 = 1 nM vs 1 μM and 2 μM for PPARα and PPARγ, respectively.

Características y beneficios

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información legal

Sold for research purposes under agreement from Glaxo­Smith­Kline

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000364099
0000364099
0000227852
0000232794
0000232793

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