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Merck

C6445

Sigma-Aldrich

Colato de sodio hydrate

BioXtra, ≥99%

Sinónimos:

Ácido 3α,7α, 12α-trihidroxi-5β-colan-24-oico sodium salt, Ácido colálico sodium salt

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About This Item

Fórmula empírica (notación de Hill):
C24H39NaO5 · xH2O
Número de CAS:
Peso molecular:
430.55 (anhydrous basis)
Beilstein/REAXYS Number:
3582354
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

anionic

product line

BioXtra

assay

≥99%

form

powder

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

impurities

≤0.05% Phosphorus (P)
≤0.1% Insoluble matter

CMC

9-15 mM (20-25°C)

solubility

H2O: 1 M, clear, faintly yellow to yellow

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

HLB

18

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1

InChI key

MUVVIYFKOVLQHL-RCVKHMDESA-M

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General description

Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins.

Application

Sodium cholate hydrate has been used in a study to assess infiltration of pressurized promoter solutions in a mesoporous silica.
Sodium cholate hydrate has been used:
  • as a component of biofilm growth media along with tryptic soy broth (TSB) to test the effects of each bile salt on biofilm formation
  • as a detergent to study its effect on cannabinoid receptor 1 (CB1) detection by western blot
  • as a promoter to prepare solution B for the synthesis of tungsten disulfide (WS2) on a SiO2/Si wafer

Features and Benefits

  • pH range 5-8
  • Suitable for membrane technology and culture media

hcodes

Hazard Classifications

Aquatic Chronic 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Infiltration of pressurized promoter solutions in a mesoporous silica
Punyamurtula and Qiao
Microporous Mater., 103, 5-5 (2007)
Fang Fang et al.
Journal of bacteriology, 191(18), 5743-5757 (2009-07-14)
Commensal lactobacilli frequently produce bile salt hydrolase (Bsh) enzymes whose roles in intestinal survival are unclear. Twenty-six Lactobacillus salivarius strains from different sources all harbored a bsh1 allele on their respective megaplasmids. This allele was related to the plasmid-borne bsh1
Mavis Jiarong Li et al.
Current protocols in protein science, 98(1), e100-e100 (2019-11-21)
Lipid nanodiscs provide a native-like lipid environment for membrane proteins, and they have become a valuable platform for the study of membrane biophysics. A range of biophysical and biochemical analyses are enabled when membrane proteins are captured in lipid nanodiscs.
F Peter Guengerich et al.
Nature protocols, 4(9), 1245-1251 (2009-08-08)
Cytochrome P450 (P450) enzymes are important in the metabolism of steroids, vitamins, carcinogens, drugs and other compounds. Two of the commonly used assays in this field are the measurements of total P450 and NADPH-P450 reductase in biological preparations. A detailed
Volkan K Köseoğlu et al.
Infection and immunity, 87(7) (2019-04-17)
Shigella flexneri is an intracellular bacterial pathogen that invades epithelial cells in the colonic mucosa, leading to bloody diarrhea. A previous study showed that S. flexneri forms biofilms in the presence of bile salts, through an unknown mechanism. Here, we

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