C1145

Cholesterol–PEG 600

• Sinónimos: Cholesterol, water soluble from sheep, Cholesteryl-polyethylene glycol 600 sebacate, Polyethylene glycol 600 mono(cholesteryl) ether sebacate, Polyoxyethyl-cholesteryl sebacate
• Número de CAS: 69068-97-9
• MDL number: MFCD00151772
• UNSPSC Code: 41141804
• eCl@ss: 39023139
• NACRES: NA.77

Propiedades

• form: solid
• extent of labeling: ≥20% cholesterol
• color: light yellow
• solubility: H₂O: 60 mg/mL
• shipped in: dry ice
• storage temp.: −20°C

Descripción

General description

Cholesterol is one of the important constituent of all membranes. It is made up of a hydrophobic, planar, a polar hydroxyl group, fused-ring nucleus and a short hydrocarbon tail.

Application

Cholesterol-PEG 600 has been used to evaluate its ability to induce apoptosis in vascular smooth muscle cells. It has also been used to restore cholesterol following depletion by methyl β-cyclodextrin.

Biochem/physiol Actions

Cholesterol acts as an antecedent of steroid hormones. It plays a key role in fetal growth and in brain development.

Physical form

semisolid to solid

Preparation Note

Prepared by method of Proksch, G.J., and Bonderman, D.P., Clin. Chem., 24, 1924 (1978).

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)