Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

C0742

Sigma-Aldrich

CKI-7 dihydrochloride

≥98% (HPLC), solid, CK1 inhibitor

Sinónimos:

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C11H12ClN3O2S · 2HCl
Número de CAS:
1177141-67-1
Peso molecular:
358.67
MDL number:
MFCD00897689
UNSPSC Code:
12352200
PubChem Substance ID:
24724430
NACRES:
NA.77

product name

CKI-7 dihydrochloride, ≥98% (HPLC), solid

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to light tan

solubility

H2O: >5 mg/mL

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChI key

JUAVTXYOCISSSL-UHFFFAOYSA-N

Biochem/physiol Actions

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

Caution

Material is hygroscopic

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Rahat S Azfar et al.
JAMA dermatology, 150(6), 601-607 (2014-03-14)
Mobile teledermatology may increase access to care. To determine whether mobile teledermatology in human immunodeficiency virus (HIV)-positive patients in Gaborone, Botswana, was reliable and produced valid assessments compared with face-to-face dermatologic consultations. Cross-sectional study conducted in outpatient clinics and public
K M Surapaneni et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 65(1), 67-74 (2014-03-14)
Oxidative stress is one of the key mechanisms responsible for liver damage and disease progression in non-alcoholic steatohepatitis (NASH). Antioxidants try to combat the oxidative stress and minimise the oxidative stress. In this study, the comparative effect of pioglitazone, quercetin
Saulat Jahan et al.
Saudi medical journal, 35(3), 298-303 (2014-03-14)
To determine the major research priorities in the field of Primary Health Care (PHC) in Qassim, Saudi Arabia. The study was a cross-sectional survey including academicians, researchers, and PHC program managers in Qassim. A self-administered questionnaire was used as the
Lindsay H Ryan et al.
Journal of behavioral medicine, 37(6), 1108-1117 (2014-03-14)
Using a nationally representative sample of couples aged 51+ in the United States (N = 1,923 couples), the current study investigated whether both partners' perceptions of relationship support and strain are associated with an individual's self-rated health and functional limitations. The sample
Martina Weber et al.
The American journal of clinical nutrition, 99(5), 1041-1051 (2014-03-14)
Early nutrition is recognized as a target for the effective prevention of childhood obesity. Protein intake was associated with more rapid weight gain during infancy-a known risk factor for later obesity. We tested whether the reduction of protein in infant
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico