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Key Documents

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B7688

Sigma-Aldrich

PiB

≥98% (HPLC)

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About This Item

Fórmula empírica (notación de Hill):
C22H18N2O8
Número de CAS:
64005-90-9
Peso molecular:
438.39
MDL number:
MFCD00333607
UNSPSC Code:
12352200
PubChem Substance ID:
329773301
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 1-2 mg/mL (warmed)

storage temp.

2-8°C

SMILES string

O=C(C1=C2C(C3=CC=C24)=C(C(N(CC(OCC)=O)C3=O)=O)C=C1)N(CC(OCC)=O)C4=O

InChI

1S/C22H18N2O8/c1-3-31-15(25)9-23-19(27)11-5-7-13-18-14(8-6-12(17(11)18)20(23)28)22(30)24(21(13)29)10-16(26)32-4-2/h5-8H,3-4,9-10H2,1-2H3

InChI key

WNKQGFNIIHNGQM-UHFFFAOYSA-N

Biochem/physiol Actions

PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to destabilization of the transcription factor Nanog, which is required for maintenance of embryonic stem cell cultures.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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