B4750

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride

trypsin substrate

• Sinónimos: BANA, N_α-Benzoyl-DL-arginine-2-naphthylamide hydrochloride
• Fórmula empírica (notación de Hill): C₂₃H₂₅N₅O₂ · HCl
• Número de CAS: 913-04-2
• Peso molecular: 439.94
• Beilstein: 3823291
• Número CE: 213-015-4
• Número MDL: MFCD00038940
• Código UNSPSC: 12352204
• ID de la sustancia en PubChem: 24891699
• NACRES: NA.32

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥98% (TLC)
• Formulario: powder
• solubilidad: DMF: 50 mg/mL, clear, colorless to faintly yellow
• temp. de almacenamiento: 2-8°C
• cadena SMILES: Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
• Clave InChI: BNGRKDJZQIGWQF-UHFFFAOYSA-N

Descripción

Aplicación

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin. It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.

Acciones bioquímicas o fisiológicas

N_α-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain. BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens. Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.

Sustratos

A chromogenic substrate for trypsin.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)