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Y0001458

Piretanide for system suitability

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Piretanide, 4-Phenoxy-3-(1-pyrrolidinyl)-5-sulfamoylbenzoic acid

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About This Item

Fórmula empírica (notación de Hill):
C17H18N2O5S
Número de CAS:
55837-27-9
Peso molecular:
362.40
Código UNSPSC:
41116107
NACRES:
NA.24
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grado

pharmaceutical primary standard

familia API

piretanide

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

[S](=O)(=O)(N)c1c(c(cc(c1)C(=O)O)N3CCCC3)Oc2ccccc2

InChI

1S/C17H18N2O5S/c18-25(22,23)15-11-12(17(20)21)10-14(19-8-4-5-9-19)16(15)24-13-6-2-1-3-7-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,20,21)(H2,18,22,23)

Clave InChI

UJEWTUDSLQGTOA-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Piretanide for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

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Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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V Homuth et al.
The American journal of cardiology, 72(9), 666-671 (1993-09-15)
To test the dose responses of piretanide, ramipril, and their combination in patients with essential hypertension, a prospective, randomized, double-blind, placebo-controlled trial was conducted in 480 patients. Twelve separate groups were studied: placebo, piretanide 3 mg, piretanide 6 mg, ramipril
N Takamura et al.
Pharmaceutical research, 13(7), 1015-1019 (1996-07-01)
The purpose of this study was to investigate the binding mechanism of loop diuretics with HSA and to characterize the binding site on HSA. Quantitative analysis of potential interaction between ligands bound to HSA was performed by equilibrium dialysis and
F Pourageaud et al.
British journal of pharmacology, 131(6), 1211-1219 (2000-11-18)
1. Relaxing effect of loop diuretics, piretanide and furosemide in comparison with acetylcholine (ACh) was investigated in guinea-pig isolated mesenteric resistance arteries. 2. Concentration-response curves to ACh (0.001 - 10 microM) and diuretics (0.0001 - 1 microM) were constructed in
P Hannaert et al.
Naunyn-Schmiedeberg's archives of pharmacology, 365(3), 193-199 (2002-03-08)
It is generally assumed that bumetanide possesses some selectivity for the renal Na-K-Cl cotransporter NKCC2, although the results are scarce in the literature and comparisons were done with extra-renal NKCC1 at its basal, almost silent state. Here we investigated NKCC2/NKCC1
R Prestel et al.
Transplant international : official journal of the European Society for Organ Transplantation, 9 Suppl 1, S437-S441 (1996-01-01)
Postischemic kidney function may be influenced by donor conditioning. The sulfamoyl-benzoate "piretanide" (P) is a diuretic agent with an inhibitory effect on the luminal Na-K-2CL-transporter system in the ascending part of the loop of Henle. A clinical pilot study demonstrated
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