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Key Documents

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Y0001136

Lovastatin for peak identification

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Lovastatin, Mevinolin

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About This Item

Fórmula empírica (notación de Hill):
C24H36O5
Número de CAS:
75330-75-5
Peso molecular:
404.54
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lovastatin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

InChI

1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

InChI key

PCZOHLXUXFIOCF-BXMDZJJMSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lovastatin for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

1370600

Lovastatin, United States Pharmacopeia (USP) Reference Standard

1370611

Lovastatin Related Compound A, United States Pharmacopeia (USP) Reference Standard

L0790000

Lovastatin, European Pharmacopoeia (EP) Reference Standard

PHR1285

Lovastatin, Pharmaceutical Secondary Standard; Certified Reference Material

1370655

Lovastatin Impurity Identification Mixture, United States Pharmacopeia (USP) Reference Standard

1236833

Lovastatin Epimer Mixture, United States Pharmacopeia (USP) Reference Standard

1443216

Mevastatin, United States Pharmacopeia (USP) Reference Standard

PHR2240

Mevastatin/Lovastatin Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2278

Lovastatin Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2279

Lovastatin Impurity D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2277

Lovastatin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Health hazard
GHS08

signalword

Warning

Hazard Classifications

Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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Chia-Hao Chen et al.
International journal of pharmaceutics, 444(1-2), 18-24 (2013-01-29)
Lovastatin, categorized as a class II compound according to the Biopharmaceutics Classification System, is mainly responsible for the blood cholesterol lowering effect of red yeast rice (RYR). The aim of this study was to compare the dissolution rate, physical state
Emily K Osterweil et al.
Neuron, 77(2), 243-250 (2013-01-29)
Many neuropsychiatric symptoms of fragile X syndrome (FXS) are believed to be a consequence of altered regulation of protein synthesis at synapses. We discovered that lovastatin, a drug that is widely prescribed for the treatment of high cholesterol, can correct
Patricia A Reis et al.
PLoS pathogens, 8(12), e1003099-e1003099 (2013-01-10)
Cerebral malaria (CM) is the most severe manifestation of Plasmodium falciparum infection in children and non-immune adults. Previous work has documented a persistent cognitive impairment in children who survive an episode of CM that is mimicked in animal models of
Chen-Huan Yu et al.
Carbohydrate polymers, 94(1), 56-62 (2013-04-03)
Two major fractions (RLP-1 and RLP-2) were obtained by purifying the crude polysaccharides extracted from a traditional Chinese herb Rosae Laevigatae Fructus. The average molecular weight of RLP-1 and RLP-2 was 21.5 kDa and 16.1 kDa, respectively. Monosaccharide analysis indicated
Kimberly A Hartwell et al.
Nature chemical biology, 9(12), 840-848 (2013-10-29)
Efforts to develop more effective therapies for acute leukemia may benefit from high-throughput screening systems that reflect the complex physiology of the disease, including leukemia stem cells (LSCs) and supportive interactions with the bone marrow microenvironment. The therapeutic targeting of
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