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Merck

Y0000475

Carboprost trometamol

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15- methylprosta-5,13-dien-1-oic acid with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Carboprost tromethamine

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About This Item

Fórmula empírica (notación de Hill):
C25H47NO8
Número de CAS:
Peso molecular:
489.64
Número MDL:
Código UNSPSC:
41116107
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

carboprost

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

−20°C

cadena SMILES

NC(CO)(CO)CO.O[C@H]1[C@H](C([C@H](C1)O)\C=C/[C@@](O)(CCCCC)C)C\C=C\CCCC(=O)O

InChI

1S/C21H36O5.C4H11NO3/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25;5-4(1-6,2-7)3-8/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25);6-8H,1-3,5H2/b7-5+,14-12-;/t16-,17?,18+,19-,21-;/m0./s1

Clave InChI

UMMADZJLZAPZAW-QFXCEMDRSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Carboprost trometamol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

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L A Levine et al.
Cancer, 66(2), 242-245 (1990-07-15)
The treatment of cyclophosphamide-induced hemorrhagic cystitis has been difficult, with overall poor results using intensive and costly therapy. The authors evaluated the treatment of this problem in four patients with prostaglandin intravesical therapy. Each patient had failed to respond to
H Abdel-Aleem et al.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 42(3), 247-250 (1993-09-01)
To compare carboprost trometamol with methylergometrine in managing the third stage of labor. One hundred and fifty parturient women were randomly assigned to use carboprost trometamol or methylergometrine immediately after delivery. Both the duration of the third stage and the
Combined bladder and uterine rupture following prostaglandin-induced midtrimester abortion: an unreported event.
Umber Agarwal et al.
Acta obstetricia et gynecologica Scandinavica, 82(10), 974-975 (2003-09-06)
Kai On Chu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 857(1), 83-91 (2007-08-19)
The two synthetic prostaglandin analogues, carboprost and misoprostol, are used extensively in obstetric and gynaecological practice. Our recent research of these compounds' use for intra-umbilical injection to treat adherent placenta necessitated their storage in solution for 3-4 days. This raised
D M Kranc et al.
The Journal of urology, 148(4), 1326-1330 (1992-10-01)
Recently, prostaglandins have been shown to be effective agents for the treatment of cyclophosphamide-induced hemorrhagic cystitis. Among the prostaglandins studied is carboprost tromethamine, a PGF2a analog. To determine the effectiveness of carboprost tromethamine therapy on the urothelium, we induced hemorrhagic

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