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F0700000

Furosemide

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid, 5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoic acid

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About This Item

Fórmula empírica (notación de Hill):
C12H11ClN2O5S
Número de CAS:
54-31-9
Peso molecular:
330.74
MDL number:
MFCD00010549
UNSPSC Code:
41116107
PubChem Substance ID:
329799665
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

furosemide

manufacturer/tradename

EDQM

mp

220 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl

InChI

1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)

InChI key

ZZUFCTLCJUWOSV-UHFFFAOYSA-N

Gene Information

human ... SLC12A1(6557)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Furosemide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Inhibits ion co-transport in the kidney.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

1287008

Furosemide, United States Pharmacopeia (USP) Reference Standard

F0702000

Furosemide impurity A, European Pharmacopoeia (EP) Reference Standard

1287020

Furosemide Related Compound A, United States Pharmacopeia (USP) Reference Standard

1287030

Furosemide Related Compound B, United States Pharmacopeia (USP) Reference Standard

Y0001493

Furosemide for peak identification, European Pharmacopoeia (EP) Reference Standard

BP547

Furosemide, British Pharmacopoeia (BP) Reference Standard

PHR1816

Furosemide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

BP074

4-Chloro-5-sulfamoylanthranilic acid, British Pharmacopoeia (BP) Reference Standard

PHR2457

2,4-Dichlorobenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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K M Ho et al.
Anaesthesia, 65(3), 283-293 (2010-01-21)
Furosemide, a potent loop diuretic, is frequently used in different stages of acute kidney injury, but its clinical roles remain uncertain. This review summarises the pharmacology of furosemide, its potential uses and side effects, and the evidence of its efficacy.
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