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Merck

936987

Sigma-Aldrich

DTBPF Pd G3 ChemBeads

new

Sinónimos:

1,1′-Bis(di-tert-butylphosphino)ferrocene Pd G3

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About This Item

Fórmula empírica (notación de Hill):
C39H57FeNO3P2PdS
Peso molecular:
844.15
UNSPSC Code:
12352100

form

solid

Quality Level

composition

, 4-6 wt. % (loading of catalyst)

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst

mp

87-150  °C ((decomposition))

functional group

phosphine

SMILES string

CC(P(c1cccc1)C(C)(C)C)(C)C.CC(P(c2cccc2)C(C)(C)C)(C)C.NC3=C(C4=CC=CC=C4[Pd]OS(C)(=O)=O)C=CC=C3.[Fe]

InChI

1S/2C13H22P.C12H10N.CH4O3S.Fe.Pd/c2*1-12(2,3)14(13(4,5)6)11-9-7-8-10-11;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;;/h2*7-10H,1-6H3;1-6,8-9H,13H2;1H3,(H,2,3,4);;/q;;;;;+1/p-1

Inchi Key

AGXLTHQKOWPGBX-UHFFFAOYSA-M

General description

DTBPF Pd G3 is a versatile palladium precatalyst developed by Buchwald group. It is widely employed in various cross-coupling reactions involving the formation of C-C, C-N, C-O, C-F, C-CF3, and C-S bonds. Precatalysts effectively generate active catalytic species for use in various reactions.

Application

For general uses, product is also available in powdered form (804975)

Features and Benefits

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

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Referencia del producto
Descripción
Precios

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ana L Aguirre et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 27(51), 12981-12986 (2021-07-08)
High-throughput experimentation (HTE) methods are central to modern medicinal chemistry. While many HTE approaches to C-N and Csp2 -Csp2 bonds are available, options for Csp2 -Csp3 bonds are limited. We report here how the adaptation of nickel-catalyzed cross-electrophile coupling of
Noah P Tu et al.
Angewandte Chemie (International ed. in English), 58(24), 7987-7991 (2019-03-21)
Technologies that enable rapid screening of diverse reaction conditions are of critical importance to methodology development and reaction optimization, especially when molecules of high complexity and scarcity are involved. The lack of a general solid dispensing method for chemical reagents

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