324744-M

Elastase Inhibitor II

The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Sinónimos: Elastase Inhibitor II, HNE Inhibitor, MeOSuc-AAPA-CMK, MSACK
• Fórmula empírica (notación de Hill): C₂₀H₃₁ClN₄O₇
• Peso molecular: 474.94
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥99% (TLC)
• form: lyophilized solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• color: white
• solubility: DMSO: 10 mg/mL; methanol: soluble
• storage temp.: −20°C

Descripción

General description

A potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His⁵⁷ and Ser¹⁹⁵ in the HNE in the presence of this inhibitor.

A potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His⁵⁷ and Ser¹⁹⁵.

Biochem/physiol Actions

Primary Target
Human neutrophil elastase (HNE)

Warning

Toxicity: Standard Handling (A)

Sequence

MeOSuc-Ala-Ala-Pro-Ala-CMK

Reconstitution

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Navia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem.262, 17178.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable