Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

165304

Sigma-Aldrich

D-(–)-2-Amino-5-phosphonopentanoic Acid

≥97% (HPLC), solid, NMDA receptor antagonist, Calbiochem®

Sinónimos:

D-(–)-2-Amino-5-phosphonopentanoic Acid, D-AP5, NMDA Antagonist II, APV, D-APV, 2-APV, D-2-amino-5-phosphonovalerate

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C5H12NO5P
Número de CAS:
79055-68-8
Peso molecular:
197.13
MDL number:
MFCD00078839
UNSPSC Code:
12352106
NACRES:
NA.77

product name

D-(–)-2-Amino-5-phosphonopentanoic Acid, Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.

Quality Level

100

assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)
protect from light

color

white

solubility

dilute aqueous base: 1 mg/mL
water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1

InChI key

VOROEQBFPPIACJ-SCSAIBSYSA-L

General description

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist. Also inhibits the capsaicin-induced release of substance P from spinal cord.
Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used competitive NMDA receptor antagonist.

Biochem/physiol Actions

Cell permeable: no
Primary Target
NMDA receptor antagonist
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Malcangio, M., et al. 1998. Br. J. Pharmacol. 125, 1625.
Schulte, M.K., et al. 1994. Brain Res. 649, 203.
Davis, S., et al. 1992. J. Neurosci. 12, 21.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Los clientes también vieron

Slide 1 of 1

1 of 1

Picrotoxin powder

Sigma-Aldrich

P1675

Picrotoxin

Jing Zhou et al.
eLife, 10 (2021-03-05)
Callosal projections from primary somatosensory cortex (S1) are key for processing somatosensory inputs and integrating sensory-motor information. How the callosal innervation pattern in S1 is formed during early postnatal development is not clear. We found that the normal termination pattern
Yu-Hong Zhang et al.
Cell stem cell, 28(8), 1483-1499 (2021-04-23)
The hypothalamus contains an astounding heterogeneity of neurons that regulate endocrine, autonomic, and behavioral functions. However, its molecular developmental trajectory and origin of neuronal diversity remain unclear. Here, we profile the transcriptome of 43,261 cells derived from Rax+ hypothalamic neuroepithelium
Hitomi Abe et al.
iScience, 25(3), 103927-103927 (2022-03-15)
Understanding the molecular mechanisms of gene regulation is pivotal for understanding how cells establish and modify their identities and functions. Multiple transcription factors (TFs) coordinate to alter gene expression in cells; however, a method to quantitatively analyze the activity of

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico