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Key Documents

16-308

Sigma-Aldrich

Anti-Myc Tag Antibody, clone 9E10, Alexa Fluor 488 conjugate

clone 9E10, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.43

biological source

mouse

Quality Level

conjugate

ALEXA FLUOR 488

antibody form

purified antibody

antibody product type

primary antibodies

clone

9E10, monoclonal

species reactivity (predicted by homology)

all

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MYC(4609)

Specificity

Myc and recombinant proteins containing the Myc epitope tag

Immunogen

Synthetic peptide corresponding to amino acids 408-437 of the Leucine zipper region of human Myc (AEEQKLISEEDLLRKRREQLKHKLEQ-LRNS)

Application

Research Category
Epitope Tags & General Use
Research Sub Category
Epitope Tags
This Anti-Myc Tag Antibody, clone 9E10, Alexa Fluor 488 conjugate is validated for use in WB, IC for the detection of Myc Tag.

Quality

routinely evaluated by immunocytochemistry on myc-tagged recombinant protein

Target description

varies

Physical form

Protein G Purified

Storage and Stability

1 year at 4°C from date of shipment

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Alexa Fluor is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ashwani Sharma et al.
Traffic (Copenhagen, Denmark), 22(10), 332-344 (2021-08-22)
Smith-Lemli-Opitz syndrome (SLOS) is a congenital and developmental malformation syndrome associated with defective cholesterol biosynthesis. It is characterized by accumulation of 7-dehydrocholesterol (the immediate biosynthetic precursor of cholesterol in the Kandutsch-Russell pathway) and an altered cholesterol to total sterol ratio.
Xavier Charest-Morin et al.
Peptides, 60, 71-79 (2014-08-17)
Based on the known fact that the parathyroid hormone (PTH) might be extended at its C-terminus with biotechnological protein cargoes, a vector directing the secretion of PTH1-84 C-terminally fused with the antigenic epitope myc (PTH-myc) was exploited. The functional properties
Benjamin J Tillotson et al.
PloS one, 10(12), e0145820-e0145820 (2015-12-30)
The equilibrium binding affinity of receptor-ligand or antibody-antigen pairs may be modulated by protonation of histidine side-chains, and such pH-dependent mechanisms play important roles in biological systems, affecting molecular uptake and trafficking. Here, we aimed to manipulate cellular transport of
Simone Eggert et al.
Cellular and molecular life sciences : CMLS, 77(24), 5223-5242 (2020-02-18)
Endocytosis of the amyloid precursor protein (APP) is critical for generation of β-amyloid, aggregating in Alzheimer's disease. APP endocytosis depending on the intracellular NPTY motif is well investigated, whereas involvement of the YTSI (also termed BaSS) motif remains controversial. Here
Arsen S Hunanyan et al.
Human gene therapy, 32(7-8), 405-419 (2021-02-13)
Alternating Hemiplegia of Childhood (AHC) is a devastating autosomal dominant disorder caused by ATP1A3 mutations, resulting in severe hemiplegia and dystonia spells, ataxia, debilitating disabilities, and premature death. Here, we determine the effects of delivering an extra copy of the

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